THE TRUTH HURTS
PACIRA'S CLAIM: EXPAREL
®
provides patient-focused pain control for up
to 72 hours.
3
THE FACTS: Based on further analysis of the data,
6
between 12–72
hours there was minimal to no difference in mean pain
intensity between EXPAREL
®
and saline (placebo).
4-5
PACIRA'S CLAIM: The only single-dose local analgesic to reduce or eliminate
opioids with pain control for up to three days.
3
THE FACTS: The clinical benefi t of the attendant decrease in opioid
consumption was not demonstrated.
2-3
Saline therapy
(placebo) was favored between 12–72 hours.
5
Get the facts and download studies about EXPAREL
®
at factvsfi ction.info or call 1-800-448-3569
for more information.
The truth behind EXPAREL
®
(bupivacaine liposome injectable suspension)
1
What is EXPAREL®, EXPAREL® Website. www.exparel.com/what-is-exparel.shtml. Created May 2, 2008. Updated December 16, 2013. Accessed February 4, 2014.
2
Exparel® [prescribing information]. Parsippany,
NJ: Pacira Pharmaceuticals, Inc.; 2011.
3
EXPAREL. Advertisement. Outpatient Surgery1 Nov. 2013:57-58. Print.
4
Golf M, Daniels SE, Onel E. A Phase III, randomized, placebo-controlled trial of DepoFoam® bupivacaine
(extended-release bupivacaine local analgesic) in bunionectomy. Adv Ther. Sep 2011;28(9):776-788.
5
Gorfi ne SR, Onel E, Patou G, et al. Bupivacaine Extended-Release Liposome Injection for Prolonged Postsurgical
Analgesia in Patients Undergoing Hemorrhoidectomy: A Multicenter, Randomized, Double-blind, Placebo-controlled trial. Dis Colon Rectum. Dec. 2011;54(12):1552-1559.
6
Data on File.
EXPAREL® is a registered trademark of Pacira Pharmaceuticals Inc. I-Flow*, LLC, A Kimberly-Clark Health Care Company. ON-Q* Pain Relief System *Registered trademark or trademark of Kimberly-Clark Worldwide Inc. © 2014 KCWW All rights reserved. RX Only. MK-00652
Effective post-op pain management.
For over 3.5 million patients and counting.
Controllable. Long-lasting. Proven.
6
Promotional claims position EXPAREL
®
as the only single-dose local analgesic to reduce
or eliminate opioids with pain control for up to three days with no need for catheters or
pumps.
1-2
Sound too good to be true? It is.
Every
day
without
costs
you
more
6
Every
day
without
costs
you
more
A K I M B E R L Y - C L A R K H E A L T H C A R E C O M P A N Y
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