Outpatient Surgery Magazine, providing current information on Surgical Services, Surgical Facility Administration, Outpatient Surgery News and Trends, OR Excellence and more.
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5 Days 4 Days 2 Days 3 Days 1 Day 12 Hours EXPAREL ® (bupivacaine liposome injectable suspension) is promoted as providing pain control that lasts for up to 72 hours without the need for catheters and pumps. 4 In fact, their two pivotal studies tell a different story. 2-3,5 We feel it is important that you know the facts. A K I M B E R L Y - C L A R K H E A L T H C A R E C O M P A N Y FACT VS FICTION Every day without costs you more 1 Every day without • Using limited studies and cumulative data, EXPAREL ® claims that a single injection can provide up to three days of "patient-focused pain control." 4 Yet, in a pivotal bunionectomy study, it is no more effective than a placebo beyond 12 hours. 1-2 • EXPAREL ® is not titratable. 6 – Cannot control fl ow rate – Cannot turn on or off as needed • In a pivotal study, after 12 hours there was no attendant decrease in morphine consumption. 3 ON-Q* has demonstrated effectiveness across multiple procedures in over 150 studies. We have provided over 3.5 million patients with effective, safe, personalized pain relief for up to fi ve days, not just 24 hours. 1 ON-Q* Proven. Controllable. Long-lasting. 1 Get the facts and download studies about EXPAREL ® at factvsfi ction.info/os2 or call 1.800.448.3569 for more information. EXPAREL's studies only demonstrate 12 hours of pain relief. 1-3 1 Data on fi le. 2 Golf M, Daniels SE, Onel E. Phase III, randomized, placebo controlled trial of DepoFoam! bupivacaine (extended-release bupiv acaine local analgesic) in bunionectomy. Adv Ther. Sep 2011;28(9):776-788. Golf M, Daniels SE, Onel E. A Phase III, randomized, placebo controlled trial of DepoFoam® bupivacaine (extended-release bupivacaine local analgesic) in bunionectomy. Adv Ther. Sep 2011;28(9):776-788. 3 Gorfi ne SR, Onel E, Patou G, et al. Bupivacaine Extend- ed-Release Liposome Injection for Prolonged Postsurgical Analgesia in Patients Undergoing Hemorrhoidectomy: A Multicenter,Randomized, Double-blind, Placebo-controlled Trial. Dis Colon Rectum. Dec 2011;54(12):1552-1559. ed-Release Liposome Injection for Prolonged Postsurgical Analgesia in Patients Undergoing Hemorrhoidectomy: A Multicenter,Randomized, Double-blind, Placebo-controlled Trial. Dis Colon Rectum. Dec 2011;54(12):1552-1559. 4 EXPAREL®. Advertisement. Outpatient Surgery 1 Nov. 2013: 57-58. Print. 5 EXPAREL® [prescribing information]. Parsippany, NJ: Pacira Pharmaceuticals, Inc.; 2011. 6 Ilfeld B, Liposome bupivacaine in peripheral nerve blocks and epidural injections to manage postoperative pain. Expert Opin. Pharmacther. (2013) 14(17):2421-2431. Ilfeld B, Liposome bupivacaine in peripheral nerve blocks and epidural injections to manage postoperative pain. Expert Opin. Pharmacther. (2013) 14(17):2421-2431. There are inherent risks in all medical devices. Please refer to the product labeling for Indications, Cautions, Warnings and Contraindications. Failure to follow the product labeling could directly impact patient safety. Physician is responsible for prescribing and administering medications per instructions provided by the drug manufacturer. Refer to www.ifl o.com for product safety Technical Bulletins. EXPAREL® is a registered trademark of Pacira Pharmaceuticals Inc. I-Flow*, LLC, A Kimberly-Clark Health Care Company. ON-Q* Pain Relief System *Registered trademark or trademark of Kimberly-Clark Worldwide Inc. © 2014 KCWW All rights reserved. RX Only. MK-00637 3/2014.