SIMPLICITY
DOESN'T REPLACE
EFFICACY
The truth about EXPAREL
®
(bupivacaine liposome injectable suspension)
EXPAREL
®
is promoted as providing pain control that lasts for up to 72 hours
without the need for catheters and pumps.
1
Sound too good to be true? It is.
In fact, based on further analysis of the data
4
, after 12 hours there
was minimal to no difference between EXPAREL
®
and placebo (normal saline)
treatments on mean pain intensity as demonstrated in their two pivotal studies.
2-3
5 Days
4 Days
3 Days
2 Days
1 Day
12 Hours
1
EXPAREL. Advertisement. Outpatient Surgery1 Nov. 2013:57-58. Print.
2
G o l f M , D a n i e l s S E , O n e l E . A P h a s e I I I , r a n d o m i z e d , p l a c e b o - c o n t r o l l e d t r i a l o f D e p o F o a m ! b u p i v a c a i n e ( e x t e n d e d - r e l e a s e b u p i v acaine local analgesic) in bunionectomy. Adv Ther. Sep 2011;28(9):776-788.
3
Gorfi ne SR, Onel E, Patou G, et al. Bupivacaine
Extended-Release Liposome Injection for Prolonged Postsurgical Analgesia in Patients Undergoing Hemorrhoidectomy: A Multicenter, Randomized, Double-blind, Placebo-controlled trial. Dis Colon Rectum. Dec. 2011;54(12):1552-1559.
4
Data on File.
EXPAREL
®
is a registered trademark of Pacira Pharmaceuticals Inc. I-Flow* LLC A Kimberly-Clark Healthcare Company. ON-Q* Pain Relief System *Registered trademark or trademark of Kimberly-Clark Worldwide Inc. ©2014 KCWW All rights reserved. RX Only. MK-00641 2/2014.
A K I M B E R L Y - C L A R K H E A L T H C A R E C O M P A N Y
EXPAREL's studies only demonstrate 12 hours of pain relief.
2-4
Every
day
without
costs
you
more
4
Every
day
without
costs
you
more
ON-Q*: Effective post-op pain management.
For over 3.5 million patients and counting.
Controllable. Long-lasting. Proven.
4
Contact your ON-Q* representative, or call
1-800-448-3569 for more information.
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