acetaminophen and
an NSAID. A
gabapentinoid may
also be effective,
depending on the
patient's condition
and comorbidities,
according to Dr.
Soffin.
"Although caution
with polypharmacy
should be stressed
— particularly in eld-
erly patents," she
says, "perioperative
ketamine is increas-
ingly being applied
to total knee anes-
thetic and analgesic
regimens, particular-
ly for patients with
chronic pain condi-
tions."
Exercise caution if
you add a gabapentin
to your multimodal
regimen. According to
Dr. Soffin, the risks of
gabapentin in older
age on sedation and
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1 Vallejo M. C., Mandell G. L., Sabo D. P., Ramanathan S. Postdural Puncture Headache: A Randomized
Comparison of Five Spinal Needles in Obstetric Patients 2000; Anesth. Analg, 2000; 91:916–20
2 Hong X., Yang L., WenYe S., ShunLi K., FeiFei L., Di Z., GuangZhi N., ShiQing F. Comparison of Cutting and Pencil-Point
Spinal Needle in Spinal Anesthesia regarding Postdural Puncture Headache: A Meta-Analysis 2017: Medicine 96:14 www.md-journal.com
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