The sustained-release steroids eliminate this issue. "Both are free of
preservatives and both provide a slow release into the eye," says Dr.
Hovanesian. "There have been no significant incidences of intraocular
pressure spikes."
Administering a combination of moxifloxacin and triamcinolone in
an intracameral injection works approximately 90% of the time to pre-
vent postoperative ocular inflammation and endophthalmitis, and
eliminates the need to prescribe antibiotic and steroid drops, accord-
ing to Dr. Hoffman. He says 10% patients who receive the injection
might experience inflammation and require topical steroids or
NSAIDs.
Dr. Hoffman is likely to use a subconjunctival steroid injection such
as triamcinolone in patients at high risk for endophthalmitis if he's con-
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1 Mixing, Diluting, or Repackaging Biological Products Outside the Scope of an Approved Biologics License Application Guidance for Industry
https://www.fda.gov/downloads/drugs/guidances/ucm434176.pdf
* ON-Q is a registered trademark of Avanos Medical Inc., or its affiliates. Avastin
®
is a registered trademark of Genentech, Inc.
