oids don't address —
at least not directly.
"Opioids don't take
pain away," says Dr.
Friedberg. "They just
make you not care
about it."
Patients experience
pain because of the
invasive nature of sur-
gery. "It sets off the
'wind-up phenome-
non.' Patients wake up
in pain because you
hurt them while they
were asleep."
A very specific
combination of
propofol and keta-
mine aims to elimi-
nate surgical pain
altogether, first by
hypnosis and then by
dissociation. The
combination consists
of a low, incremental
dose of propofol 50
mcg/kg (titrated to
BIS < 75 with a base-
line EMG) followed
7 8 • O U T PA T I E N T S U R G E R Y M A G A Z I N E • O C T O B E R 2 0 1 9
CONSISTENT
FLOW RATE
TOO FAST
TOO SOON
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*World Journal of Anesthesiology m2014 March 27; 311); n9-123; ISSN 221806182 lonline);
Baishideng Publishing Group Co. Note: Pumps were set to a nominal flow rate of 12 ml/hr.
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